Therapeutic and Pharmacological Potential of Azadirachta indica
Keywords:
Azadirachta indica, Antimicrobial activity, Anti-inflammatory properties, Phytochemicals, Pharmacological applicationsAbstract
Azadirachta indica (neem) is a widely recognized medicinal plant with extensive use in traditional systems such as Ayurveda. The present study highlights the therapeutic and pharmacological potential of neem based on its rich composition of bioactive compounds, including azadirachtin, nimbin, nimbidin, and quercetin. Various parts of the plant—leaves, bark, seeds, and oil—exhibit significant biological activities such as antimicrobial, anti-inflammatory, antioxidant, antidiabetic, anticancer, and immunomodulatory effects. Neem has demonstrated effectiveness against a broad spectrum of pathogens, supports blood glucose regulation, and protects against oxidative stress–induced cellular damage. Additionally, its role in promoting skin health, wound healing, and oral hygiene has been well documented. Despite its promising pharmacological profile, concerns regarding toxicity at higher doses necessitate controlled usage and further clinical validation. Overall, Azadirachta indica represents a valuable natural resource with significant potential for the development of novel therapeutic agents in modern medicine.
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